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Final Proceedings: 3rd International PEEK Meeting, April 27-28, 2017

The Implant Research Center of Drexel University and Exponent, Inc., are pleased to provide the final proceedings for the 3rd International PEEK Meeting, which was convened at The Cosmos Club, Washington, DC, USA on April 27 and 28, 2017. The purpose of the conference was to bring together engineers, scientists, regulators, and clinicians from academia, industry, and government agencies for the presentation of leading edge research on advancements in medical grade polyaryletherketone (PAEK) polymer technology and clinical applications. Although all scientific studies, clinical applications and innovations related to the broad family of medical grade PAEKs were welcome at this conference, the majority of submissions were related to implantable PEEK and its composites. Click here for more information on the final proceedings for the PEEK Meeting.

Biotribology of HXLPE on PEEK Bearings

Little is known about the biotribology of all-polymer PEEK bearings. Researchers from Philadelphia simultaneously tested a total of 100 pin-on-disk couples (n = 10 per bearing couple) consisting of three traditional metal-on-UHMWPE and seven polymer-on-polymer bearings for 2 million cycles under physiologically relevant conditions per ASTM F732. The combined wear rates of all-polymer bearing couples were not different than traditional bearing couples. The data suggest that all-polymer bearings, especially PEEK-on-HXLPE bearing couples, may represent a viable alternative to traditional bearings with respect to their wear performance.

Noteworthy in 2016: PEEK Femoral Components for TKA and Stress Shielding

A polyetheretherketone (PEEK) femoral implant has the potential to promote bone strains closer to that of natural bone as a result of its low elastic modulus compared with cobalt-chromium (CoCr). Researchers from Leeds have performed an in vitro study to determine the effect of a PEEK femoral component on local bone strains. Results of this study suggest that the strain shielding observed with the contemporary CoCr implant, consistent with clinical bone mineral density change data reported by others, may be reduced by using a PEEK implant.

Systematic Review on Biological Response of PEEK Wear Particles

Researchers from the University of Leeds performed a systematic review of the literature related to the biological response of PEEK wear particles. They found that wear particles produced by PEEK-based bearings were, in almost all cases, in the phagocytozable size range (0.1-10 microm). The studies that evaluated the biologic response to PEEK-based particles generally found cytotoxicity to be within acceptable limits relative to the UHMWPE control, but inconsistent when inflammatory cytokine release was considered.

Bone Formation with PEEK/HA Composites in a Sheep Fusion Model

Researchers from Prince of Wales Hospital in Australia investigated bone ongrowth and fusion outcomes of PEEK/HA as compared with natural PEEK in a cervical fusion model. Incorporating HA into the PEEK matrix resulted in more direct bone apposition as opposed to the fibrous tissue interface with PEEK alone in the bone ongrowth as well as interbody cervical fusions. No adverse reactions were found at the implant-bone interface for either material.

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