Featured Publications & Reports

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2010 EFORT E-Poster: Biological Activity of CFR-PEEK particles in the Murine Knee Joint

The biological response of two different varieties of PEEK compared to ultra-high-molecular-weight-polyethylene (UHMWPE) particles was performed by injections to the knee joints in mice. The results of this animal study suggest that carbon-fiber reinforced PEEK is comparable to UHMWPE in its inflammatory response. For this reason and due to its mechanical properties, CFR-PEEK may be an attractive  biomaterial for the use in arthroplasty.

2010 EFORT E-Poster: Biocompatibility of Human Osteoblast-Like Cells on PEEK

Researchers investigated the osteointegration of human osteoblast-like cells( MG 63) in cultures on the following surface-modified metallic and polymeric materials, developed for construction of artificial hip joint replacements, including metal alloys, PEEK, and UHMWPE. The data suggest that plasma-sprayed and a-C:H-coated Ti-6Al-4V, polished stainless steel AISI 316 LWM and PEEK seem to be suitable materials for constructing bone-anchoring parts of joint prostheses,while polished UHMWPE can be used for creation of articular surfaces,where the cell adhesion and growth is not desirable.

2010 EFORT E-Poster: Clinical Outcomes of PEEK-on-PEEK Cervical Total Disc Replacements

The purpose of this study was to assess the clinical and radiological outcome of single and multiple level anterior cervical decompression and disc replacement (ACDR) using new peek on peek (POP) cervical disc replacement prosthesis (NuNec™ Cervical Arthroplasty System, Pioneer Surgical Technology, München, USA). This report summarizes the 6-month follow up results, which were promising. Longer term follow-up is awaited.

2010 SFB Poster: PEEK Multifilament and Monofilament Woven Tissue Engineering Scaffolds

The aim of this work was to fabricate flexible woven PEEK scaffolds. Scaffolds were characterised in terms of their physical and mechanical properties and biologically assessed, culturing with L929 mouse fibroblasts for up to 16 days in vitro. Multifilament PEEK woven scaffolds were lighter, thinner and stronger than monofilament PEEK scaffolds. Woven PEEK scaffolds supported fibroblast cell attachment and proliferation, and ECM production. The results of this study indicate that fibrous PEEK structures have potential as scaffolds for tissue engineering.

Preparation and Tribological Properties of PEEK-UHMWPE Composites

Researchers from Nanjing University of Science and Technology have investigated PEEK composites filled with 20% UHMWPE to improve wear resistance. Tribological properties of PEEK-UHMWPE composites were investigated by block-on-ring friction and wear rig. An alloy (CoCrMo) ring and a ceramic (Si(3)N(4)) ring were used as friction pairs. The experiments were conducted under deionized water lubrication (DWL), saline lubrication (SL), and calf serum solution lubrication (CSSL). The results indicated that friction coefficients and wear of PEEK/UHMWPE composites were effectively reduced when compared with pure PEEK.

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