Featured Publications & Reports

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2010 EFORT E-Poster: Biocompatibility of Human Osteoblast-Like Cells on PEEK

Researchers investigated the osteointegration of human osteoblast-like cells( MG 63) in cultures on the following surface-modified metallic and polymeric materials, developed for construction of artificial hip joint replacements, including metal alloys, PEEK, and UHMWPE. The data suggest that plasma-sprayed and a-C:H-coated Ti-6Al-4V, polished stainless steel AISI 316 LWM and PEEK seem to be suitable materials for constructing bone-anchoring parts of joint prostheses,while polished UHMWPE can be used for creation of articular surfaces,where the cell adhesion and growth is not desirable.

2010 EFORT E-Poster: Clinical Outcomes of PEEK-on-PEEK Cervical Total Disc Replacements

The purpose of this study was to assess the clinical and radiological outcome of single and multiple level anterior cervical decompression and disc replacement (ACDR) using new peek on peek (POP) cervical disc replacement prosthesis (NuNec™ Cervical Arthroplasty System, Pioneer Surgical Technology, München, USA). This report summarizes the 6-month follow up results, which were promising. Longer term follow-up is awaited.

2010 SFB Poster: PEEK Multifilament and Monofilament Woven Tissue Engineering Scaffolds

The aim of this work was to fabricate flexible woven PEEK scaffolds. Scaffolds were characterised in terms of their physical and mechanical properties and biologically assessed, culturing with L929 mouse fibroblasts for up to 16 days in vitro. Multifilament PEEK woven scaffolds were lighter, thinner and stronger than monofilament PEEK scaffolds. Woven PEEK scaffolds supported fibroblast cell attachment and proliferation, and ECM production. The results of this study indicate that fibrous PEEK structures have potential as scaffolds for tissue engineering.

Preparation and Tribological Properties of PEEK-UHMWPE Composites

Researchers from Nanjing University of Science and Technology have investigated PEEK composites filled with 20% UHMWPE to improve wear resistance. Tribological properties of PEEK-UHMWPE composites were investigated by block-on-ring friction and wear rig. An alloy (CoCrMo) ring and a ceramic (Si(3)N(4)) ring were used as friction pairs. The experiments were conducted under deionized water lubrication (DWL), saline lubrication (SL), and calf serum solution lubrication (CSSL). The results indicated that friction coefficients and wear of PEEK/UHMWPE composites were effectively reduced when compared with pure PEEK.

Evaluation of CFR-PEEK Dental Implants using Finite Element Analysis

The aim of this study was to compare, using the three-dimensional finite element method, the stress distribution in the peri-implant support bone of distinct models composed of PEEK components and implants reinforced with 30% carbon fiber (30% CFR-PEEK) or titanium. In simulations with a perfect bonding between the bone and the implant, the 30% CFR-PEEK presented higher stress concentration in the implant neck and the adjacent bone, due to the decreased stiffness and higher deformation in relation to the titanium. However, 30% CFR-PEEK implants and components did not exhibit any advantages in relation to the stress distribution compared to the titanium implants and components.

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