Featured Publications & Reports

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2008 WBC Conference Poster: Bone Formation Potential of Human Primary Osteoblasts on PEEK and Titanium

Researchers from the University of Connecticut Health Center have investigated bone formation on PEEK and Ti surfaces using a primary human osteoblast in vitro model. The in-vitro performance of two PEEK-based biomaterials (unfilled or carbon fiber reinforced PEEK-OPTIMA) presented to the human bone cells as either injection molded or machined, was comparable to that of Grade 1 cpTi commonly used for implants. All in-vitro parameters (adhesion, proliferation, alkaline phosphatase activity, synthesis of bone matrix proteins and mineralization) appear to be influenced by the surface finish of the material as generated using common manufacturing techniques such as polishing, injection molding or machining.

2008 WBC Conference Poster: Wear Analysis of a PEEK Interpositional Knee Arthroplasty

Researchers from Advanced Bio-Surfaces have developed test methods for evaluating the wear behavior of PEEK and CFR-PEEK against bone. Human femoral cadaver bone, synthetic delrin analogues, and a “BoneSim” analog were evaluated. The investigators concluded that BoneSim may provide a worst-case scenario for PEEK-on-bone testing of interpositional prostheses.

2008 WBC Conference Poster: Tribological Performance of CFR-PEEK against CoCrMo

Wear tests were performed at Durham University on PEEK-OPTIMA and carbon fibre reinforced PEEK-OPTIMA (CFR-PEEK) against cobalt chrome molybdenum (CoCrMo) to assess the potential of this material combination for use in orthopaedic implants. Multi-directional pin-on-plate wear machines were used. CFR-PEEK against CoCrMo (HC or LC) provided low wear rates. This study gives confidence in the likelihood of this material combination performing well in orthopaedic applications.

2008 WBC Conference Poster: Wear Assessment of Self-Mating PEEK Disc Arthroplasty

The purpose of this study was to provide a comprehensive wear assessment of self mating PEEK-OPTIMA (PEEK) for use in lumbar disc arthroplasty applications under different motion profiles, test frequencies and environmental conditions. Testing of PEEK-on-PEEK disc arthroplasties was performed on a six-station spine wear simulator. The results suggest that self-mating PEEK does not undergo orientation softening at the wear surface. The long term wear properties of self-mating PEEK were found to be relatively low.

2008 WBC Conference Poster: Preliminary Investigation of Implantable PEEK Fiber

This preliminary study examines whether PEEK-OPTIMA could be processed at an industrially relevant scale into a fiber form. A further goal was to also examine if the fiber would possess some of the suitable mechanical and cytocompatible properties beneficial for textile based medical devices. PEEK monofilaments were manufactured at 50 and 100μm diameter. Mechanical properties were comparable to the commonly used PET. Excellent cytocompatibilty was observed. This study demonstrates that PEEK-OPTIMA can be processed into mono and multifilaments, suitable for use in a variety of textile technologies.

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