Featured Publications & Reports

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Noteworthy in 2014: Dental Applications of PEEK

Since the first PEEK dental studies started to appear in the published scientific literature around 2008, PEEK continues to be investigated as a biomaterial for dental applications. In this in vitro study, researchers from Munich Dental School in Germany examined the interface strength of dental cements with PEEK after plasma treatment. The use of methyl methacrylate (MMA)-based adhesives allows bonding between PEEK and self-adhesive resin cements. Plasma treatment has no impact on bond to resin cements. Click here to see a brief commentary of the article by the Editor of the PEEK Lexicon.

Noteworthy from 2013: CFR-PEEK Composites for Trauma

This compreshensive study by researchers from Tel-Aviv explores the static and dynamic mechanical behavior and wear particles from trauma devices fabricated from CFR-PEEK composites. Tibial nails, dynamic compression plates, proximal humeral plates, and distal radius plates were analyzed in this study and compared with metallic devices. The researchers concluded that the CFR-PEEK trauma products were similar, biomechanically, to metallic trauma devices already in clinical use.

Noteworthy from 2013: Porous SPEEK Nanotextured Scaffolds for Tissue Engineering

Researchers from the University of Hong Kong have developed a family of porous, sulfonated-PEEK (SPEEK) scaffolds to promote tissue integration. Two types of SPEEK scaffolds were developed using a combination of exposure to sulfuric acid, followed by water immersion and rinsing with water or acetone. The cytocompatibility of the constructs was sensitive to the presence of residual sulfuric acid. Cell attachment was found to be enchanced with the nanotextured, SPEEK scaffolds. 

Noteworthy for 2013: PEEK Meshes for Pelvic Organ Prolapse Repair

The aim of this study was to evaluate candidate polymer fiber meshes, including monofilament PEEK, as potential candidates for POP meshes. Meshes were assessed for their structural characteristics using multi-axial test methods. The new fabricated mesh designs were of similar architecture, but with some improved mechanical properties, compared to clinical POP meshes. 

Noteworthy from 2013: Elevated Cytokine Expression of CFR-PEEK Particles

In a follow-on study to previous research on the biocompatiblity of CFR-PEEK wear particles in a mouse knee model, researchers from the University Hospital of Munich have conducted immunohistochemistry analyses of particulate pitch- and PAN-based PEEK composites. Cytokine expression (IL-1Beta, IL-6, and TNF-alpha) was examined in the synovial layers, adjacent bone marrow and the cartilage. They found increased cytokine expression of the CFR-PEEK particles as compared with UHMWPE particles and controls, raising new questions about its suitability for UKA applications. 

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