Featured Publications & Reports

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Noteworthy from 2013: Elevated Cytokine Expression of CFR-PEEK Particles

In a follow-on study to previous research on the biocompatiblity of CFR-PEEK wear particles in a mouse knee model, researchers from the University Hospital of Munich have conducted immunohistochemistry analyses of particulate pitch- and PAN-based PEEK composites. Cytokine expression (IL-1Beta, IL-6, and TNF-alpha) was examined in the synovial layers, adjacent bone marrow and the cartilage. They found increased cytokine expression of the CFR-PEEK particles as compared with UHMWPE particles and controls, raising new questions about its suitability for UKA applications. 

Noteworthy from 2013: Retrieval Analysis of PEEK Rods

The purpose of this study was to analyze explanted PEEK rod spinal systems in the context of their clinical indications. Researchers from Drexel University evaluated damage to the implant and histological changes in explanted periprosthetic tissues. This study documents the surface changes and tissue reactions for retrieved PEEK rod stabilization systems. Permanent indentations by the set screws and pedicle screws were the most prevalent observations on the surface of explanted PEEK rods.

Program and Abstracts: First International PEEK Meeting, Philadelphia PA, in April 2013

The Implant Research Center of Drexel University in collaboration with Exponent, Inc. is pleased to announce the proceedings for the 1st PEEK International Meeting, which convened at the Union League, Philadelphia, PA, USA, on Thursday and Friday, April 25 and 26, 2013. The purpose of the meeting was to bring together engineers, scientists, and clinicians from academia and industry and present leading edge research on advancements in medical grade PEEK technology and clinical applications. Click here for details on the final program and abstracts for the meeting. 

ASTM Round Robin Results on DSC of PEEK

The ASTM task group for PEEK conducted a round robin to quantify the repeatability and reproducibility of DSC measurements of thermal transitions in PEEK was conducted between 2011 and 2012. Eight labs participated and all provided data for the analysis, as summarized in the technical memorandum.

Revision and Retriveal Analysis of PEEK Rods for Posterior Fusion and Motion Presevation

The purpose of this study was to develop a classification system for the initial surgical indications, intention to treat, reasons for revision, and complications for the PEEK rod systems for comparison with metallic fusion rod systems. A secondary goal of this study was to establish the incidence of hardware-related complications for the revised PEEK rod systems. We sought to determine if flexible PEEK rod systems are associated with unique clinical risks or failure modes that differ from traditional Ti rods, which are considered to be comparatively “rigid” by clinicians.

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