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PEEK-Optima HA Enhanced Biomaterial: Pre-Clinical in vivo and in-vitro Characterization

  This presentation reviews current in-vivo and in-vitro studies of Hydroxyapatite-enhanced PEEK.

Macromolecular and Morphological Characterization of Medical Grade PEEK Polymers

In this study, we examined the morphology of four medical grade PEEK polymers using a variety of characterization techniques to determine whether there were significant differences between their molecular and nanostructures.

Biological Response to Ceramic-on-Carbon-Fibre-Reinforced-PEEK from Total Hip Replacements

This study aims to investigate the wear performance of a ceramic on CFR-PEEK total hip replacement in a 10 million cycle cimulator study. The wear debris products were characterized and compared to the debris generated in an UHMWPE-on-ceramic THR. Then the osteolytic potential of the CFR-PEEK and UHMWPE wear debris was assessed.

Effect of Contact Pressure on the Wear of PEEK and CFR-PEEK Materials Against Metallic Counterfaces

 Total joint replacement has been a successful surgical intervention for many years, with the majority of bearing joints having ultra-high molecular weight polyethylene as an articulating material. However, concerns remain regarding wear debris induced osteolysis and the longevity of TJR as patient demands change.

Effects of Mold Temperature on the Properties of HA Whisker Reinforced PEEK

Porous and bioactive polyetheretherketone (PEEK) scaffolds have potential to replace metallic scaffolds for biologic fixation of permanent implants adjacent to trabecular bone, such as interbody spinal fusion devices. The objective of this study was to investigate the effects of the mold temperature and PEEK powder on the mechanical properties and crystallinity of hydroxyapatite (HA) whisker reinforced PEEK scaffolds prepared using compression molding and porogen leaching. The results of this study suggested that HA reinforced PEEK scaffolds should be compression molded at 370-375°C. The apparent compressive modulus, yield strength, and yield strain for scaffolds molded at 370-375°C was 75-92 MPa, 2.0-2.2 MPa, and 2.5-3.6%, respectively, which was within the range exhibited by human vertebral trabecular bone.

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